Research

CCIV has five integrative focus areas that are designed to build new collaborations, leading to sustainable research programs, new grant opportunities and important discoveries. 

Microbial Pathogenesis Program

This program includes laboratories focused on basic biology and immunology of the following pathogens:

  • HIV/AIDS
  • Measles virus
  • Respiratory syncytial virus (RSV)
  • Viral and Bacterial Diarrheal Pathogens
  • Cryptosporidiosis
  • Malaria
  • Structural basis of host-pathogen interactions

​Innate Immunity Program

The innate immunity program focuses on basic aspects of the immune response to foreign antigens, including the early responses that change the adaptive immune responses. Novel adjuvants (stimulants of the innate response that can enhance vaccine efficacy) are one area of focus of this program.

​Neonatal/Developmental Immunity Program

Vaccine responses in young infants are complicated by an immature immune system and sometimes by the presence of maternal antibody. This program focuses on unique aspects of immunity in the developing fetus and the newborn infant, with the goal of enhancing the efficacy of vaccines given to infants.

Global Infectious Diseases Program

The Global Infectious Diseases Program is focused on clinical research and interventions for pathogens that are major causes of childhood mortality in the developing world. Current areas of research by CCIV investigators in this Program include epidemiology and treatment for malaria and rotavirus vaccine efficacy in the developing world.

​Vaccine Development and Testing Program

This program spans the spectrum of the vaccine development process, from the design and testing of new vaccines in the lab to the performance of human clinical trials. The program currently is focusing on vaccines against malaria, rhinovirus, respiratory syncytial virus, HIV/AIDS, Ebola, Zika, and influenza.

For more information on research from Emory University's Department of Pediatrics' Infectous Diseases Division, in which many CCIV researchers are housed, please click here