• Dr. Park Awarded RO1 “Mechanisms of ER71/ETV2-Regulated Vascularization”

    July 14, 2017

    The transcription factor ER71 (also known as ETV2) is a critical regulator of FLK1 whose function is essential for vessel development and post-natal angiogenesis. The overall goal of this proposal is to investigate mechanisms by which ER71 regulates Flk1 expression and neovascularization by employing mouse genetic models and mouse embryonic stem cell differentiation system. Our preliminary studies provide compelling evidence showing its potent and unexpected functions in the mechanism of vascular endothelial cell generation and revascularization in the adult, and thus outcome from this application will provide a new research platform which could lead to the development of new therapeutic strategies for cardiovascular diseases.

  • Rajneesh Jha Wins 2nd Place Basic Science Poster Award

    June 09, 2017

    Rajneesh Jha Wins 2nd Place Basic Science Poster Award at 2017 Southeastern Pediatric Research Conference "Metabolic Approach to Promote the Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes" Cinsley Gentillon, Rajneesh Jha, Antonio Rampoldi, Wen-Mei Yu, Shuzhao Li, Bill Liang, Andrei Todor,…

  • Aline Yonezawa Receives BME Outstanding Departmental Service Award

    April 25, 2017

    Six graduate students and one faculty advisor were honored at this year’s third annual BME Graduate Awards event hosted by the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory.  The Outstanding Departmental Service…

  • Kids with Heart Defects Face Learning Challenges thumbnail Photo

    Kids with Heart Defects Face Learning Challenges

    February 21, 2017

    Children born with heart defects face learning challenges and inadequate special education assistance in elementary school, according to a new study.  Matthew Oster, MD featured in AHA news.

  • Davis lab featured on the Feb 2017 cover of Circulation Research thumbnail Photo

    Davis lab featured on the Feb 2017 cover of Circulation Research

    February 09, 2017

    Abstract Rationale: Studies have demonstrated that exosomes can repair cardiac tissue post–myocardial infarction and recapitulate the benefits of cellular therapy. Objective: We evaluated the role of donor age and hypoxia of human pediatric cardiac progenitor cell …

  • “The mitochondrial calcium uniporter in the heart: energetics and beyond” Jennifer Kwong, PhD

    February 01, 2017

    Ca2+ and mitochondria are inextricably linked to cardiac function and dysfunction. Ca2+ is central to cardiac excitation–contraction coupling and stimulates mitochondrial energy production to fuel contraction. Under pathological conditions of dysregulated Ca2+ cycling, mitochondrial Ca2+overload activates cellular death pathways.