Faculty Directory

Hans E. Grossniklaus, MD

Hans E. Grossniklaus, MD headshot

Professor of Ophthalmology and Pathology
Emory University School of Medicine

Director of Ocular Oncology Service
Director, Section of Ocular Oncology and Pathology
Director, LF Montgomery Laboratory of Ophthalmic Pathology
Emory Eye Center

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PHONE: 404-778-4611
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As the founding director of the ocular oncology and pathology service, my laboratory focuses on ocular oncology, including drug delivery to primary ocular retinoblastoma and melanoma. I have expertise in ocular
retinoblastoma and melanoma including animal models of these diseases. I see and treat patients with these tumors including performing surgery and giving intravitreal injections. In this project, I will 1) test suprachoroidal and intravitreal topotecan in a rabbit and obtain ocular tissue for biodistribution; 2) test suprachoroidal and intravitreal topotecan for treatment of retinoblastoma subretinal or vitreous seeds in our rabbit model of retinoblastoma; 3) test suprachoroidal or intravitreal topotecan in patients with subretinal or vitreous seeds of retinoblastoma. I am in a unique position to carry out these investigations, as my laboratory developed the rabbit model of retinoblastoma which is the only model that develops retinoblastoma seeds, I participated in the original project that developed microneedles for suprachoroidal drug delivery, I am an ophthalmic pathologist who routinely evaluates the pathology of retinoblastoma, and I am an ocular oncologist who evaluates and treats patients.


Eye tumors
Macular degeneration (AMD)
Ocular malignancies
Retinal disease

Research Center(s)