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Emergency Physician–Administered Propofol Sedation: A Report From the Pediatric Research Consortium

Emergency Physician–Administered Propofol Sedation: A Report on 25,433 Sedations From the Pediatric Sedation Research Consortium

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Michael D. Mallory, MD, MPH, Amy L. Baxter, MD, Daniel J. Yanosky, PhD, Joseph P. Cravero, MD, for the Pediatric Sedation Research Consortium From Pediatric Emergency Medicine Associates, Children’s Healthcare of Atlanta at Scottish Rite Hospital, Atlanta, GA (Mallory, Baxter); the Department of Mathematics and Statistics, Kennesaw State University, Kennesaw, GA (Yanosky); and the Department of Anesthesiology and Pediatrics, Dartmouth Hitchcock Medical Center, Lebanon, NH (Cravero)

Editor’s Capsule Summary

What is already known on this topic

Emergency physicians frequently administer
propofol to accomplish deep procedural sedation.

What question this study addressed

What is the adverse effect profile of propofol
administration by emergency physicians?

What this study adds to our knowledge

Serious adverse effects were rare and without adverse
outcome in this series of 25,433 pediatric propofol
administrations by emergency physicians.
Emergency physician–led sedation services
composed the majority of sedations in this sample.

How this is relevant to clinical practice

This large study strongly corroborates the safety of
propofol administration by emergency physicians.