Overview
Dr. Meacham is the director of the Fertility Preservation & Reproductive Health Program and endocrine service for the Aflac Cancer and Blood Disorders Center. For over 30 years, her focus has been cancer survivor research, which included cardiovascular health and metabolic syndromes. As part of her research, she was also the site PI for the Childhood Cancer Survivor Study until 2019.
Her current research interests are in reproductive health including: female and male late effects of cancer therapy, fertility status assessments and infertility risk communication.
Learn more about our Fertility Preservation Program.
Pediatric Psychology
Pediatric Oncology
Brooke Cherven, PhD, MPH, RN, CPON
Sunia Hoey, RN
James Ludemann, RN, CPHON, OCN
Rebecca Williamson-Lewis, MPH
Pediatric Endocrinology
Megan Pruett, PNP, RN
Pediatric and Adolescent Gynecology
Pediatric Urology
Carrie Bedient, MD, Reproductive Endocrine and Infertility, Private Practice, NV
Hahn Cottrell, MD, Reproductive Endocrine and Infertility, Private Practice, MI
Karen Effinger, MD, MSc, Pediatric Hematology/Oncology, Faculty, Emory University, Atlanta, GA
Swati Elchuri, MD, Pediatric Endocrinology, Private Practice, Twelve Oaks, CA
Sabrina Gerkowicz, MD, Reproductive Endocrine and Infertility, Private Practice, Miami, FL
Heather Hipp, MD, Reproductive Endocrine and Infertility, Faculty, Emory University, Atlanta, GA
Audrey Marsidi, MD, Reproductive Endocrine and Infertility, Faculty, Emory Healthcare, Atlanta, GA
D. Austin Schirmer, MD, Reproductive Endocrine and Infertility, Faculty, Emory University, Atlanta, GA
Reproductive Health
Mulder RL, Font-Gonzalez A, Hudson MM, van Santen HM, Loeffen EAH, Burns KC, Quinn GP, van Dulmen-den Broeder E, Byrne J, Haupt R, Wallace WH, van den Heuvel-Eibrink MM, Anazodo A, Anderson RA, Barnbrock A, Beck JD, Bos AME, Demeestere I, Denzer C, Di Iorgi N, Hoefgen HR, Kebudi R, Lambalk C, Langer T, Meacham LR, Rodriguez-Wallbert K, Stern C and Stutz-Grunder E. Recommendations for fertility preservation for female childhood, adolescent and young adult cancer patients: a report from the PanCareLIFE consortium in collaboration with the International Late Effects of Childhood Cancer Guideline Harmonization. Lancet Oncol. 2021 Feb;22(2):e45-e56. doi: 10.1016/S1470-2045(20)30594-5
Van der Kooi ALF, Mulder RL, Hudson MM, Kremer LCM, Skinner R, Constine L, van Dorp W, van Dulmen-den Broeder E, Falck Winther J, Wallace WHB, Waugh J, Woodruff TK, Anderson RA, Armenian SH, Bloemenkamp K, Critchley H, Demoor C, Ehrhardt M, Green D, Grohman W, Iwahata Y, Krishna J, Laven JSE, Levitt G, Meacham LR, Miller E, Mulders A, Polanco A, Ronckers C, Samuel A, vanden Heuvel-Ebrink MM and Levine JM. Recommendations for counseling and surveillance of obstetric risks for female survivors of childhood, adolescent, and young adult cancer: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group. Accepted A m J Obstet Gynecol. 2020 Jun 2:S0002-9378(20)30614-1. doi: 10.1016/j.ajog.2020.05.058. Online ahead of print. PMID: 32502557
Meacham LR, Burns K, Orwig K and Levine J. Standardizing Risk Assessment for Treatment Related Gonadal Insufficiency and Infertility in Childhood Adolescent and Young Adult Cancer: the PIN Risk Stratification System. J Adolesc Young Adult Oncol. 2020 May 26. doi: 10.1089/jayao.2020.0012. Online ahead of print. PMID: 32456570
Elchuri SV, Quarmyne M, Haight A, Cottrell H, Meacham LR. Longitudinal Description of Gonadal Functions in Sickle Cell Patients treated with Alkylator based Conditioning Regimens for Bone Marrow Transplant. J Pediatr Hematol Oncol. 2020 Mar 20. doi: 10.1097/MPH.0000000000001782. [Epub ahead of print] PMID: 32205784
George SA, Lewis RW, McKenzie L, Cherven B, Patterson BC, Effinger KE, Mertens AC, Meacham LR. Assessment of ovarian function in adolescents and young adults after childhood cancer treatment – How accurate are young adult/parent proxy-reported outcomes? Pediatr Blood Cancer. 2019 Dec;66(12):e27981. doi: 10.1002/pbc.27981. Epub 2019 Sep 10. PMID: 3150237
George, S, Williamson-Lewis R, Schirmer D, Effinger K, Spencer JB, Mertens AC, Meacham LR. Early Detection of Ovarian Dysfunction by anti-Mullerian Hormone in Adolescent and Young Adult Aged Survivors of Childhood Cancer. J Adolesc Young Adult Oncol. 2019 Feb;8(1):18-25. doi: 10.1089/jayao.2018.0080. Epub 2018 Oct 3. PMID: 30281375
Skinner R, Mulder RL, Kremer LC, Hudson MM, Constine LS, Bardi E, Boekhour A, Borgman-Staudt A, Brown MC, Cohn R, Dirksen U, Giwercman A, Ishiguro H, Jahnukainen K, Kenney LB, Loonen JJ, Meacham L, Neggers S, Nussey S, Peterson C, Shnorhavorian M, van den Huevel MM, van Santen HM, Wallace WHB, Green DM. Recommendations for Gonadotoxicity Surveillance in Male Childhood, Adolescent and Young Adult Cancer Survivors: A Report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in Collaboration with the PanCareSurFup consortium. Lancet Oncol. 2017 Feb;18(2):e75-e90. doi: 10.1016/S1470-2045(17)30026-8. Review. PMID: 28214419
Van Dorp W, Mulder RL, Kremer LC, Hudson MM, van den Heuvel-Eibrink MM, van den Berg MH, Levine JM, van Dulmen-den Broeder E, di Iorgi N, Albanese A, Armenian SH, Bhatia S, Constine SL, Corrias A, Deans R, Dirksen U, Gracia C, Hjorth L, Kroon L, Lambalk CB, Landier W, Levitt G, Leiper A, Meacham L, Mussa A, Neggers SJ, Oeffinger KC, Revelli A, van Santen HM, Skinner R, Toogood A, Wallace WH, Haupt R. Recommendations for Premature Ovarian Insufficiency Surveillance for Female Childhood, Adolescent and young Adult Cancer Survivors: A Report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in Collaboration with the PanCareSurFup Consortium. J Clin Oncol. 2016 Jul 25. pii: JCO643288. [Epub ahead of print] Review. PMID: 27458300
Ritenour, CW, Seidel KD, Leisenring W, Mertens AC, Wasilewski-Masker K, Shnorhavorian M, Sklar CA, Whitton JA, Stoval M, Constine LS, Armstrong GT, Robison LL and Meacham LR. Erectile Dysfunction in Male Survivors of Childhood Cancer—A Report from the Childhood Cancer Survivor Study. J Sex Med. 2016 Apr 21. pii: S1743-6095(16)30054-6. doi: 10.1016/j.jsxm.2016.03.367. [Epub ahead of print] PMID: 27117527
Wasilewski-Masker K, Seidel KD, Leisenring W, Mertens A, Shonorhavorian M, Ritenour C, Stoval M, Green DM, Sklar CA, Armstrong GT, Robison LL, Meacham LR. Male Infertility in long-term survivors of pediatric cancer: a report from the Childhood Cancer Survivor Study. J Cancer Survivor. 2014 Sep;8(3):437-47. doi: 10.1007/s11764-014-0354-6. Epub 2014 Apr 8. PMID: 24711092
Risk Communication
Meacham LR, Burns K, Orwig K and Levine J. Standardizing Risk Assessment for Treatment Related Gonadal Insufficiency and Infertility in Childhood Adolescent and Young Adult Cancer: the PIN Risk Stratification System. J Adolesc Young Adult Oncol. 2020 May 26. doi: 10.1089/jayao.2020.0012. Online ahead of print. PMID: 32456570.
Meacham LR, Williamson Lewis R, Cherven BO, Effinger KE, Klosky J, and Gilleland-Marchak J. Educational Intervention to Address Infertility Related Knowledge Gaps Among Adolescent and Young Adult (AYA) Survivors of Childhood Cancer. Submit J Adolesc Young Adult Oncol. 2020 Feb 18. doi: 10.1089/jayao.2019.0156. [Epub ahead of print] PMID: 32069427
Marchak JG, Cherven B, Williamson Lewis R, Edwards P, Meacham LR, Palgon M, Escoffery C, Mertens AC. User-centered design and enhancement of an electronic personal health record to support survivors of pediatric cancer. Support Care Cancer. 2019 Dec 18. doi: 10.1007/s00520-019-05199-w. [Epub ahead of print] PMID: 31853699
Gilleland Marchak J, Siedel KD, Mertens AC, Ritenour CWM, Wasilewski-Masker K, Leisenring W, Sklar CA, Ford J, Krull K, Stovall M, Robison LL, Armstrong GT, Meacham LR. Perceptions of risk for infertility among male survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer. 2018 Apr 17. doi: 10.1002/cncr.31343. [Epub ahead of print] PMID: 29663341
Cardiovascular Health
Sachdeva R, Stratton K, Cox DE, Armenian SH, Bhat A, Border WL, Leger KJ, Leisenering WM, Meacham LR, Sadak KT, Siwanandam S,Chow EJ, Nathan PC. Challenges Associated with retrospective analysis of left ventricle function using clinical echocardiograms from a multicenter research study. Echocardiography. 2021 Jan 24. doi: 10.1111/echo.14983. Online ahead of print.
Chen Y, Chow E, Oeffinger KC, Border WL, Leinsenring WM, Meacham LR, Mulrooney DA, Sklary CS, Stoval M, Robison LL, Armstrong GT, Yasui Y. Traditional cardiovascular risk factors and individual prediction of cardiovascular events in childhood cancer survivors. J Natl Cancer Inst. 2020 Mar 1;112(3):256-265. doi: 10.1093/jnci/djz108. PMID: 31161223
Friedman DN, Moskowitz C, Hilden P, Howell RM, Weathers RE, Smith SA, Wolden SL, Tonorezos ES, Mostoufi-Moab S, Chow EJ, Chou JF, Whitton JA, Leisenring WM, Robison LL, Armstrong GT, Oeffinger KC, Sklar CA. Radiation Dose and Volume to the Pancreas and Subsequent Risk of Diabetes Mellitus: A Report from the Childhood Cancer Survivor Study. J Natl Cancer Inst. 2019 Jul 22. pii: djz152. doi: 10.1093/jnci/djz152. [Epub ahead of print] PMID: 31329225
Rose-Felker K, Kellerman MS, Sacheva R, Meacham LR, Effinger KE, Border WL. Improving Pediatric Cardiologist Awareness about the Needs of childhood Cancer Survivors: Results of a Directed Educational Initiative. Cardiol Young. 2019 Jun;29(6):808-812. doi: 10.1017/S104795111900088X. Epub Jul 8. PMID: 31280730
Other Endocrine Late Effects
George SA, Effinger KE and Meacham LR. Endocrine Sequelae in Childhood Cancer Survivors. Endocrinol Metab Clin North Am. 2020 Dec;49(4):565-587. doi: 10.1016/j.ecl.2020.07.001. Epub 2020 Oct 13. PMID: 33153668
Van Santen HM, Chemaitilly W, Meacham LR, Tonoreze E, Moustoufi-Moab S. Endocrine Health in Childhood Cancer Survivors. Pediatr Clin North Am. 2020 Dec;67(6):1171-1186. doi: 10.1016/j.pcl.2020.08.002. PMID: 33131540
Sklar CS, Zoltan A, Chematilly W, Cohen LE, Follin C, Meacham LR, Murad H. Hypothalamic-Pituitary and Growth Disorders in Survivors of Childhood Cancer: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018 Jun 29. doi: 10.1210/jc.2018-01175. [Epub ahead of print] PMID: 29982476
Chemaitilly W, Cohen LE, Mostoufi-Moab S, Patterson BC, Meacham LR, van Santen HM, Sklar CA. Endocrine Late Effects in Childhood Cancer Survivors. J Clin Oncol. 2018 Jun 6:JCO2017763268. doi: 10.1200/JCO.2017.76.3268. [Epub ahead of print] PMID: 29874130
Chow EJ, Chen Y, Hudson MM, Feijen EAM, Kremer LC, Border WL, Green DM, Meacham LR, Mulrooney DA, Ness KK, Oeffinger KC, Ronckers CM, Sklar CA, Stovall M, van der Pal HJ, van Dijk IWEM, van Leeuwen FE, Weather RE, Robison LL, Armstrong GT, Yasui Y. Prediction of ischemic heart disease and stroke among childhood cancer survivors. J Clin Oncol. 2018 Jan 1;36(1):44-52. doi: 10.1200/JCO.2017.74.8673. Epub 2017 Nov 2. PMID: 29095680
Moustoufi-Moab S, Seidel K, Leisenring W, Armstrong G, Oeffinger K, Stovall M, Meacham L, Green D, Weathers R, Ginsberg J, Robison L, Sklar C. Endocrine Abnormalities Increase with Age in Survivors of Childhood Cancer: A Report from the Childhood Cancer Survivor Study. 2016 J Clin Oncol. 2016 Sep 20;34(27):3240-7. doi: 1200/JCO.2016.66.6545. Epub 2016 Jul 5. PMID: 27382091
NCI: R01 CA218389-01
SurvivorLink: Scalability of an Electronic Personal Health Record for Cancer Survivors and Caregivers at Pediatric Cancer Centers
Role: Co-Investigator
PI: Mertens and Escoffrey
NHLBI: K23 HL143164-01
STELLAR – Sickle Cell Transplant Evaluation of Long-Term and Late Effects Registry
Role: Co-Investigator
PI: Krishnamurti