Emory's Asthma Research Program conducts multiple NIH-funded pediatric asthma studies. See below for more information.
Our program is staffed by a team of experienced clinicians, research specialists, and clinical coordinators dedicated to promoting research in asthma treatment and prevention.
The Emory Asthma Research team works to provide resources to asthma patients and families in the form of research study drugs, investigational studies, and asthma action plans. The ultimate goal of our efforts is to find the most innovative and effective treatment plans for those affected by asthma while pursuing the possibility of preventing asthma in high-risk children.
The PARK Clinical Research Study: Preventing Asthma in High-Risk Kids
Most children 2-3 years of age with allergy and wheezing illnesses develop asthma.
The purpose of this 4-year study is to see if a medicine, omalizumab (Xolair®), can prevent children from developing asthma. Omalizumab blocks the body’s response to allergens such as dust, animal dander, and pollen. This medication is already approved for treating asthma in children 6 years of age and older.
We are looking for children 24 through 47 months of age with:
Wheezing episodes in the past year AND
A parent or sibling with a diagnosis of asthma
Participation in the PARK study includes the following:
Monthly telephone calls
Monthly injection visits for 2 years
Questionnaires, physical exams and blood tests throughout the 4 years study.
Allergen skin testing, breathing tests and urine, nasal and house dust sample collections.
Up to $2640 compensation for the completion of the entire study plus travel
Study medication and supplies provided.
***For more information about this study please contact Alison Corace, BSN, RN***
***For more information about this study please contact Carrie Mason, BS, RRT***
A Clinical Research Study to Understand Asthma Attacks in Children
More than half of all children with asthma will have an asthma “attack” each year. All children with asthma are different, but the treatments for asthma the same. We want to change this.
Children with asthma rarely have one symptom. Instead, most children have clusters of symptoms that may reflect different types of inflammation. For example, some children wheeze and have trouble breathing. Other children may cough or have airway mucous every day or at night. These symptom clusters are different for different children. However, current treatment for children for asthma is the same. We want to change this. This study will see whether children with different symptom clusters have different responses to asthma treatment. This study will also see if symptom clusters predict the occurrence of future asthma attacks.
We are looking for children 8 through 17 years of age with at least one asthma attack in the previous year for this clinical research study.
Participation in the Symptom Clusters study includes the following:
Five study visits over 48 weeks
Telephone contacts with a Registered Nurse
A steroid injection (triamcinolone) at the first visit only to assess steroid treatment response
Questionnaires, physical exams and breathing tests at each visit.
Blood tests for allergies and inflammation at visits 1, 2, and 5
Studies of airway mucous at visits 1,2 and 5 in older children
Compensation for time and travel
Clinicaltrials.gov Identifier: NCT04002362
CDC Asthma page: https://www.cdc.gov/asthma/default.htm
FDA Asthma Fact Sheet: https://www.fda.gov/consumers/minority-health-and-health-equity/asthma-fact-sheet
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