The Emory Asthma Research team works to provide resources to asthma patients and families in the form of research study drugs, investigational studies, and asthma action plans. The ultimate goal of our efforts is to find the most innovative and effective treatment plans for those affected by asthma while pursuing the possibility of preventing asthma in high-risk children.

The PARK Clinical Research Study: Preventing Asthma in High-Risk Kids

Most children 2-3 years of age with allergy and wheezing illnesses develop asthma.

The purpose of this 4-year study is to see if a medicine, omalizumab (Xolair®), can prevent children from developing asthma. Omalizumab blocks the body’s response to allergens such as dust, animal dander, and pollen. This medication is already approved for treating asthma in children 6 years of age and older.

 

We are looking for children 24 through 47 months of age with:

 Wheezing episodes in the past year AND

 A parent or sibling with a diagnosis of asthma

 

Participation in the PARK study includes the following:

 Monthly telephone calls

 Monthly injection visits for 2 years

 Questionnaires, physical exams and blood tests throughout the 4 years study.

 Allergen skin testing, breathing tests and urine, nasal and house dust sample collections.

 Up to $2640 compensation for the completion of the entire study plus travel

 Study medication and supplies provided.

***For more information about this study please contact Alison Corace, BSN, RN***


***For more information about this study please contact Carrie Mason, BS, RRT***

 

A Clinical Research Study to Understand Asthma Attacks in Children

More than half of all children with asthma will have an asthma “attack” each year. All children with asthma are different, but the treatments for asthma the same. We want to change this.

Children with asthma rarely have one symptom. Instead, most children have clusters of symptoms that may reflect different types of inflammation. For example, some children wheeze and have trouble breathing. Other children may cough or have airway mucous every day or at night. These symptom clusters are different for different children. However, current treatment for children for asthma is the same. We want to change this. This study will see whether children with different symptom clusters have different responses to asthma treatment. This study will also see if symptom clusters predict the occurrence of future asthma attacks.

We are looking for children 8 through 17 years of age with at least one asthma attack in the previous year for this clinical research study.

 

Participation in the Symptom Clusters study includes the following:

 Five study visits over 48 weeks

 Telephone contacts with a Registered Nurse

 A steroid injection (triamcinolone) at the first visit only to assess steroid treatment response

 Questionnaires, physical exams and breathing tests at each visit.

 Blood tests for allergies and inflammation at visits 1, 2, and 5

 Studies of airway mucous at visits 1,2 and 5 in older children

 Compensation for time and travel

 

 

 

 

Clinicaltrials.gov Identifier: NCT04002362

Clinical Research Principal Investigators and Co-Investigators                  

Dr. Anne Fitzpatrick                                                     

Dr. Jocelyn Grunwell                                              

 

Clinical Research Nurses and Coordinator

Morgan Nicholls, MSN, RN

Alison Corace, BSN, RN

Carrie Mason, BS, RRT

Click below to submit a question or to get in touch with one of our team's coordinators - we're here to help!

Request an Appointment

Submit a Question

Spacer Technique

Spacer with a Mask Technique

Breathing Techniques