Faculty Directory

Young-Sup Yoon, MD, PhD

Young-Sup Yoon, MD, PhD headshot

Director of Stem Cell Biology
Professor of Medicine
Division of Cardiology
Department of Medicine
Emory University School of Medicine

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PHONE: 404-727-8176
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PubMed

Research

Major interest of our team is to use stem cell technology to treat various cardiovascular diseases.

Stem Cells

• We develop and use different bone marrow-derived stem or progenitor cells for cardiovascular repair

o Bone marrow-derived multipotent stem cells (BMSC)

o Endothelial progenitor cells

o Mesenchymal stem cells

o Hematopoietic stem cells

• Target diseases

o Cardiac diseases: Myocardial infarction, chronic heart failure

o Peripheral vascular disease; PAOD (peripheral artery obstructive disease) etc

o Diabetic neuropathy

o Lymphedema

o Wound (wound healing)

• We investigate embryonic stem cells

o differentiate into endothelial cells, cardiomyocytes, lymphatic vessels

o therapeutic potential in the target diseases

• We recently started to combine technologies of biomaterial and stem cells for cardiac repair

Mechanistically, we are interested in angiogenesis, lymphangiogenesis, and cardiomyogenesis

Diabetes related research

• We work on the role of angiogenesis in diabetic complications such as heart failure, PAOD and diabetic    neuropathy

• We investigate functional defects of stem or progenitor cells in diabetes

o Currently we are studying ROS-related targets

• We are developing a strategy to rescue this impairment

Affiliate Center(s)