NIH Exploratory/Developmental Research Grant Program (Parent R21)
Deadline: Standard NIH Deadlines
Amount: The combined budget for direct costs for the two-year project period may not exceed $275,000. No more than $200,000 may be requested in any single year. The total project period may not exceed 2 years.
The Parent NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
Applications are assigned to participating Institutes and Centers (ICs) based on receipt and referral guidelines and many applications are assigned to multiple participating ICs with related research interests. Applicants are strongly encouraged to identify a participating IC that supports their area of research via the R21 IC-Specific Scientific Interests and Contact website and contact Scientific/Research staff from relevant ICs to inquire about their interest in supporting the proposed research project.
For specific information about the mission of each NIH IC, visit the List of NIH Institutes, Centers, and Offices website.
- Clinical trials not allowed, see companion FOA for clinical trial
- Applicants should note that some ICs do not accept applications through this parent R21 mechanism and/or applications proposing a clinical trial through this R21 funding opportunity announcement. If the proposed research project includes an NIH-defined research project/clinical trial that would be assigned to one of these ICs, applicants are advised to contact relevant Scientific/Research staff to discuss alternative mechanisms of support of these studies.
- Applications for Exploratory/Developmental Research Grant awards should include projects distinct from those supported through the traditional R01 activity code. For example, long-term projects, or projects designed to increase knowledge in a well-established area, are not appropriate for this FOA. Applications submitted to this FOA should be exploratory and novel. These studies should break new ground or extend previous discoveries toward new directions or applications.