Faculty Directory
Jan R Mead, PhD
Professor Emeritus
Laboratory of Biochemical Pharmacology
Department of Pediatrics
Emory University School of Medicine
EMAIL: .(JavaScript must be enabled to view this email address)
PHONE: 404-321-6111 ext.2545
Biography
Dr. Mead focuses on opportunistic infections related to HIV infection, specifically Cryptosporidium parvum. Her expertise in immunology and SCID mouse models is frequently sought through grant collaborations and interdisciplinary projects.
Research
One key focus of my laboratory has been the study of immune responses important in Cryptosporidium parvum infection, an intestinal opportunistic protozoan that can cause severe infections in HIV-infected individuals. We are interested in determining the cytokines and cell populations necessary for response and recovery and in identifying antigens that may be key in protective immune responses. We have designed several DNA vaccine constructs that are being evaluated for their protective effect in a mouse knockout model. Another area of interest for us is in identify potential drug targets and evaluating chemotherapeutic agents in cell-based and in vivo models.