Overview

Part of the Center for Clinical and Translational Research (CCTR), the Biorepository Core offers clinical sample processing and storage services for investigators conducting basic, epidemiologic, translational and clinical research related to improving child health.  The core supports investigator-initiated, center-based and disease-based research studies.  

The core also is building a bank of human blood and tissue samples from both healthy control subjects and patients with a variety of medical diagnoses. If you would like to use the Biorepository Core for an existing, previously IRB-approved study, we will provide rider language to add to your informed consent form so that a portion of your samples can be contributed to the biobank.

The Biorepository Core processes and stores the following types of human samples using standardized laboratory procedures:

  • Whole Blood for Future DNA or RNA Extraction
  • Plasma
  • Serum
  • PBMCs
  • Urine
  • Stool
  • Biopsy Tissues

All specimens are tracked electronically via a Nautilus Laboratory Information Management System (LIMS). Samples are stored in 4˚C, -80˚C, and -150˚C freezers monitored 24 hours a day/7 days a week by a Vaisala monitoring system. Clinical data for samples may be stored in REDCap, Emory's Research Electronic Data Capture system.

Please note that samples processed and stored by the core are for research purposes only. Anyone conducting child health-related research, whether internal or external to Emory, may use the Biorepository Core.

New Samples

  • Processing according to standard protocol or investigators' protocols
  • Storage in a variety of media and freezers, including liquid nitrogen
  • Distribution - We will ship and receive samples to/from external laboratories as requested by investigators.  

Samples Available for Withdrawal

  • PBMCs, plasma, whole blood, DNA, and urine from pediatric patients with immune-mediated disorders, solid organ transplant recipients and/or patients with end-stage organ disease who are awaiting organ transplant
  • Blood and urine from living kidney donors and healthy controls with renal diagnoses of rejection, stable function or viremia 
  • Clinical data can be made available upon request.

New Studies

We will be happy to provide letters of support for grant applications that would like to use the Biorepository Core. Please send your request for a letter with your project title and a brief project description to CCTRBiorepository@emory.eduClick here for a sample letter of support.

We offer a complimentary 30 minute consultation to any investigator interested in using the biorepository.  If the investigator decides to use our services, they will be charged a $50 startup fee to cover the time involved in setting up the study in LIMS and REDCap. 

After the study is set up, the following costs per sample will apply (effective July 1, 2017).  Custom or kit-based studies are charged at an hourly rate of $38 based on the specific requirements of the study.

The Biorepository Core is located on the second floor of Emory's Health Sciences Research Building (HSRB E264).  

Please use our REDCap form to submit a request.  Here you can:

  • Submit a sample for processing, storage, or processing & storage
  • Request a sample
  • Request supplies/kits for sample collection
  • Meet to discuss using the biorepository

You may also email us at CCTRBiorepository@emory.edu.  

CCTR is establishing a Molecular Clinical Trials Laboratory (MCTL) to provide support and advice on the conduct of clinical trials throughout the entire research process, from initial study design and planning through the implementation and interpretation of molecular assays of drug targets and genomic correlates of disease. Establishing the MCTL and biorepository will allow investigators to start addressing biologic correlates of chronic disease. The MCTL is being established to provide technical support and conduct of biologic assays in support of clinical trials including protein and RNA and DNA analyses as well as some cell culture assays. Please contact Brad Hanberry for more information.

Citing the Biorepository Core

The Biorepository Core is generously supported by Children's Healthcare of Atlanta and Emory University. When presenting or publishing work completed using the core, please include "Children's Healthcare of Atlanta and Emory University's Pediatric Biorepository Core" in the acknowledgments.

To determine if you should use “Children’s Healthcare of Atlanta” in your author affiliations, please see guidelines here.