Overview

Children's Clinical and Translational Discovery Core offers clinical sample processing and storage services for investigators conducting basic, epidemiologic, translational and clinical research related to improving child health.  The core supports investigator-initiated, center-based and disease-based research studies.  

The core also is building a bank of human blood and tissue samples from both healthy control subjects and patients with a variety of medical diagnoses. If you would like to use the core for an existing, previously IRB-approved study, we will provide rider language to add to your informed consent form so that a portion of your samples can be contributed to the biobank.

Children's Clinical and Translational Discovery Core processes and stores the following types of human samples using standardized laboratory procedures:

  • Whole Blood for Future DNA or RNA Extraction
  • Plasma
  • Serum
  • PBMCs
  • Urine
  • Stool
  • Biopsy Tissues

All specimens are tracked electronically via a Nautilus Laboratory Information Management System (LIMS). Samples are stored in 4˚C, -80˚C, and -150˚C freezers monitored 24 hours a day/7 days a week by a Vaisala monitoring system. Clinical data for samples may be stored in REDCap, Emory's Research Electronic Data Capture system.

Please note that samples processed and stored by the core are for research purposes only. Anyone conducting child health-related research, whether internal or external to Emory, may use the core.

New Samples

  • Processing according to standard protocol or investigators' protocols
  • Storage in a variety of media and freezers, including liquid nitrogen
  • Distribution - We will ship and receive samples to/from external laboratories as requested by investigators.  

Samples Available for Withdrawal

  • Urine from kidney transplant patients. 
  • Clinical data can be made available upon request.

New Studies

We will be happy to provide letters of support for grant applications that would like to use the core. Please send your request for a letter with your project title and a brief project description to CCTRBiorepository@emory.edu

We offer a complimentary 30 minute consultation to any investigator interested in using the core.  If the investigator decides to use our services, they will be charged a $50 startup fee to cover the time involved in setting up the study in LIMS and REDCap. 

After the study is set up, the following costs per sample will apply (effective July 1, 2017).  Custom or kit-based studies are charged at an hourly rate of $38 based on the specific requirements of the study.  

Academic Rates

Please contact Kristen Herzegh for industry rates.  

The Children’s Clinical and Translational Discovery Core is located on the second floor of Emory's Health Sciences Research Building (HSRB E264).  

Please use our REDCap form to submit a request.  Here you can:

  • Submit a sample for processing, storage, or processing & storage
  • Request a sample
  • Request supplies/kits for sample collection

For meeting requests, email us at CCTRBiorepository@emory.edu.  

The Children’s Clinical and Translational Discovery Core can also provide support and advice on the conduct of clinical trials throughout the entire research process, from initial study design and planning through the implementation and interpretation of molecular assays of drug targets and genomic correlates of disease. Establishing the MCTL and biorepository will allow investigators to start addressing biologic correlates of chronic disease. The MCTL is being established to provide technical support and conduct of biologic assays in support of clinical trials including protein and RNA and DNA analyses as well as some cell culture assays. Please contact Chris Porter  and Brad Hanberry for more information.

Citing the Children’s Clinical and Translational Discovery Core 

The Children’s Clinical and Translational Discovery Core  is generously supported by Children's Healthcare of Atlanta and Emory University. When presenting or publishing work completed using the core, please include "Children's Healthcare of Atlanta and Emory University's Children’s Clinical and Translational Discovery Core" in the acknowledgments.

To determine if you should use “Children’s Healthcare of Atlanta” in your author affiliations, please see guidelines here.