Karen A Kirby, PhD
Laboratory of Biochemical Pharmacology
Department of Pediatrics
Our research focuses on uncovering fundamental mechanisms of how viruses replicate, how they can be targeted by novel antiviral therapeutics, and how they develop resistance to antivirals. The overarching goal of our research is understand how viruses work and improve antiviral therapies for infected patients. Much of our work has focused on HIV and Hepatitis B virus (HBV). We also study Influenza virus and picornaviruses such as Enterovirus and Coxsackievirus, which affect children. We utilize a variety of tools in our lab, including structural biology, biochemical and biophysical methods, and virology.