Jan R Mead, PhD
Laboratory of Biochemical Pharmacology
Department of Pediatrics
Emory University School of Medicine
PHONE: 404-321-6111 ext.2545
One key focus of my laboratory has been the study of immune responses important in Cryptosporidium parvum infection, an intestinal opportunistic protozoan that can cause severe infections in HIV-infected individuals. We are interested in determining the cytokines and cell populations necessary for response and recovery and in identifying antigens that may be key in protective immune responses. We have designed several DNA vaccine constructs that are being evaluated for their protective effect in a mouse knockout model. Another area of interest for us is in identify potential drug targets and evaluating chemotherapeutic agents in cell-based and in vivo models.