Chunhui Xu, PhD
Director, Cardiomyocyte Stem Cell Laboratory
Department of Pediatrics
Emory University School of Medicine
Chunhui Xu, Ph.D., is an Associate Professor of Pediatrics at Emory University School of Medicine. She received her doctoral degree from the University of Georgia in Athens, Georgia and postdoctoral training from the Burnham Institute in San Diego, California.
Dr. Xu has extensive research experience on stem cells and cardiogenesis. Before joining Emory University in 2012, she conducted research on the growth and differentiation of human pluripotent stem cells (hPSCs) at Geron Corporation in Menlo Park, California. At Emory, she directs the Cardiomyocyte Stem Cell Laboratory at the Pediatric Research Alliance, a center sponsored by Children’s Health Care of Atlanta, Georgia Institute of Technology, and Emory University. Her research is focusing on human cardiomyocytes derived from human pluripotent stem cells, which hold promise for cardiac cell therapy, disease modeling, drug discovery, and the study of developmental biology. Her laboratory is collaborating with investigators in Georgia Tech, Emory University, and Children’s Healthcare of Atlanta, exploring the application of nanotechnology and tissue engineering in stem cell research. Dr. Xu has received extramural research funding from NIH (the National Institutes of Health), CASIS (the Center for the Advancement of Science in Space), and AHA (the American Heart Association).
Dr. Xu's group has made significant contribution to the field of pluripotent stem cells. Notably, they have (1) established a widely used feeder-free system for maintaining stem cells, (2) identified a role for basic fibroblast growth factor in supporting the self-renewal of undifferentiated stem cells, (3) developed a growth factor-guided method for efficient differentiation of stem cells into cardiomyocytes, (4) engineered hPSC-cardiomyocytes and established induced pluripotent stem cells (iPSCs) for disease modeling and drug discovery, and (5) demonstrated therapeutic potential of hPSC-cardiomyocytes. She has published in journals including Nature Biotechnology, Circulation Research, Biomaterials, Disease Models and Mechanisms, and Stem Cell Reports, and is an inventor or co-inventor of 16 issued U.S. patents. Several of her publications have been identified as a hot paper or among the most highly cited publications in the stem cell field.